About us

ESMS provides specialist services to support Clinical Trials and Medical Information. We’re available to cover your Medical Monitoring and emergency unblinding requirements 24 hours a day and 7 days a week, wherever you are in the world.


Our global reach means we currently support more than 300 studies and 110K patients in 80 countries, speaking over 45 different languages. We know that patient safety is paramount and we’re here to help you ensure the highest possible standards.

Our story

Our service was established in 1963, providing Medical Toxicology and Information Services within the ‘poison’s unit’ of Guy’s Hospital London. In 1996 ESMS became a new division within the unit, providing specialist medical response and emergency unblinding services for the pharmaceutical industry.

In 2007 we were recognised as a ‘centre of excellence’ during our first GCP inspection by the MHRA and in 2011 ESMS became a private limited company.

Our Core Competencies

Our experienced team has worked tirelessly to create and perfect a service that is not only continuously available but will also consistently deliver beyond regulatory requirements. Our core capabilities and services are:

  • Emergency medical response services for clinical trials 24/7/365
  • Medical monitoring and response services during every trial stage, to support subject participation and raise engagement and retention levels.
  • Reliable, cost efficient language translation support in 45 languages

We take a dynamic and flexible approach, shaping our services to accommodate your specific requirements.

Discover more about what we do and where you can find us

More About

What makes us different?

We’re always there when you need us. When you’re running a clinical trial, every emergency request for information requires an immediate response. Our experienced and qualified team can support callers quickly and efficiently, regardless of time or geographical location. Our experienced team can manage the call independently or by contacting the principal investigator or client on-call medics, if required.

Our contact centre is staffed around the clock by Information Scientists. Each holds a minimum qualification of a life-science degree such as Pharmacology, Toxicology or Biomedical Sciences. Our Information Scientists are the direct line of communication for your patients, answering the number on the patient card. If contacted by a treating physician, they are properly trained and equipped to access trial and drug information and help you avoid unnecessary code breaks. In turn, they have support from our qualified team of Senior Consultant Physicians, should clinical advice be required.

With this level of expertise available as a first response, you can rest assured that any issues will be properly evaluated and responded to, and that your patient safety will be protected at all times, day or night.

Telecoms options

No two ESMS customers are the same, which is why we offer different ways of working. If you need dedicated telephone lines, secured solely for your use, we can provide them. This might be your preferred option if you want to use our service for a portfolio of studies across several different countries and want all patients to be able to use dedicated in-country lines.

Our shared telephone lines offer a more cost-efficient but equally reliable service and are ideal for smaller or local studies. For small to mid-sized organisations, using the centralised ESMS line or integrating our telecoms service into your current solution might better suit your needs and your budget.

The benefits of using ESMS

When you need a flexible and efficient service that can be easily integrated into your existing processes, choose ESMS.

We can provide:

  • bespoke services, shaped to suit your needs
  • the option of single study use
  • full pipeline cover, with expert support at every step
  • integration with your interactive response technology (IRT)
  • dedicated in-country phone lines
  • a multilingual service covering over 45 languages.

Quality assured

Safeguarding patient confidentiality is always a priority. That’s why we’ve embedded the highest standards of information governance into ESMS culture.

Our clinical trial services comply with ICH Good Clinical Practice standards as well as all applicable regulations relating to the conduct of clinical trials. Our medical information services follow PIPA guidelines and comply with the ABPI Code of Practice. We have also undergone routine GCP inspection by the MHRA and our quality management system has been consistently certified to ISO 9001 since 2013.

With a team so committed to delivering excellence in all they do and with quality control processes in place to ensure continual improvement, it’s no wonder that we regularly receive high-praise from market-leading pharmaceutical companies during their vendor-audits.

Is it time you spoke to us about your next clinical trial?

Organisations we work with

ESMS work closely with a wide range of companies, large and small, within the Pharmaceutical and Science sector.

We focus on delivering our reliable, 24/7 robust service and personal approach.

“ESMS has prevented several unnecessary code breaks during the recruitment period.
The team work with you to produce comprehensive SOP’s and their experts are able to direct callers to more information as an alternative to unblinding where possible.”

JILL WOOD , Quality Assurance Manager, Warwick Clinical Trials.